Cardiology MCQs-8

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Most sensitive and specific test for myocardial damage

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A. Troponin I

B. CK-MB

C. Lactate dehydrogenase

D. Ischemia-modified albumin

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Which is most specific for myocardial injury?

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A. Troponin T

B. CK-MB

C. Troponin I

D. Troponin C

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Which is earliest to peak in myocardial injury?

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A. Troponin I

B. Myoglobin

C. Lactate dehydrogenase

D. Ischemia-modified albumin

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Glycogen phosphorylase isoenzyme BB isoform of the enzyme exists in

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A. Heart and Kidney

B. Heart and Brain

C. Heart and Liver

D. Heart and Pancreas

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Homocysteine is a cardiac biomarker classified as Biomarkers of

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A. Myocardial injury

B. Myocardial Necrosis

C. Hemodynamic stress

D. Markers of inflammation and prognosis

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Soluble CD40 ligand (sCD40L) is a cardiac biomarker for

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A. Myocardial injury

B. Myocardial Necrosis

C. Hemodynamic stress

D. Markers of inflammation

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	Cardiac Biomarkers	Peak level
1	Troponin	12 hours
2	Myoglobin	2 hours
3	Lactate dehydrogenase	72 hours
3	Glycogen phosphorylase isoenzyme BB	7 hours
4	CK-MB	10–24 hours

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Classification of cardiac biomarkers

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	Classification of cardiac biomarkers	Cardiac biomarkers
1	Myocardial injury – Biomarkers of myocardial necrosis	CK-MB fraction, myoglobin, cardiac troponins
2	Myocardial injury- Biomarkers of myocardial ischemia	Ischemia-modified albumin (IMA), heart-type fatty acid-binding protein (H-FABP)
3	Biomarkers of hemodynamic stress	Natriuretic peptides (NPs): atrial natriuretic peptide (ANP), N-terminal proBNP (NT-proBNP), B-type natriuretic peptide (BNP)
4	Inflammatory and prognostic markers	hs C-reactive protein (CRP), sCD40L, homocysteine

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