Bunina bodies


Bunina bodies are seen in –


A. Chickenpox

B. Parkinsonism

C. Amyotrophic lateral sclerosis

D. Multiple sclerosis



All of the following are TRUE about Bunia bodies EXCEPT –


A. Basophilic

B. Intraneuronal inclusions

C. Seen in Lower motor neurons

D. Pathologic hallmark of amyotrophic lateral sclerosis 



Bunina bodies has predilection for the which part of spinal cord?


A. Cervical

B. Thoracic

C. Lumbar

D. Upper cervical



Bunia bodies are commonly seen in all of the following EXCEPT –


A. cytoplasm

B. dendrites

C. axoplasm

D. All of the above



Bunia Bodies do not stain with –


A. Phosphotungstic acid-hematoxylin

B. Sudan black B

C. Klu¨ver-Barrera staining

D. Masson trichrome stain



Bunia Bodies – most commonly found in the motor neurons of the


  1. spinal cord
  2. brainstem nuclei

Rarely Found in-

  1. Betz cells
  2. oculomotor and Onuf nuclei
  3. non-motor neurons of the Clarke column
  4. medullary reticular formation

Bunia bodies -Present in most cases of ALS with the exception


Bunia bodies -Present in most cases of ALS with the exception of

  1. subset of familial ALS with posterior column involvement
  2. motor neuron disease with basophilic inclusions

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