Bunina bodies

Bunina bodies are seen in –

A. Chickenpox

B. Parkinsonism

C. Amyotrophic lateral sclerosis

D. Multiple sclerosis

All of the following are TRUE about Bunia bodies EXCEPT –

A. Basophilic

B. Intraneuronal inclusions

C. Seen in Lower motor neurons

D. Pathologic hallmark of amyotrophic lateral sclerosis 

Bunina bodies has predilection for the which part of spinal cord?

A. Cervical

B. Thoracic

C. Lumbar

D. Upper cervical

Bunia bodies are commonly seen in all of the following EXCEPT –

A. cytoplasm

B. dendrites

C. axoplasm

D. All of the above

Bunia Bodies do not stain with –

A. Phosphotungstic acid-hematoxylin

B. Sudan black B

C. Klu¨ver-Barrera staining

D. Masson trichrome stain

Bunia Bodies – most commonly found in the motor neurons of the

  1. spinal cord
  2. brainstem nuclei

Rarely Found in-

  1. Betz cells
  2. oculomotor and Onuf nuclei
  3. non-motor neurons of the Clarke column
  4. medullary reticular formation

Bunia bodies -Present in most cases of ALS with the exception

Bunia bodies -Present in most cases of ALS with the exception of

  1. subset of familial ALS with posterior column involvement
  2. motor neuron disease with basophilic inclusions

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