Babesia




Babesia

Babesiaalso called Nuttallia
1infects Red blood cells
2transmitted byTicks
3Babesia Protozoan
4Disease is called asBabesiosis
5babesiosis also called piroplasmosis
6Maltese-cross formRBCs- which have a tetrad structure
7Splenectomized patientsMore susceptible
8Most common piroplasmBabesia microti
9Babesiosis seen as Co-infection with Lyme Disease Co-infection
babesiosis

Morphologies of Babesia in blood smears –

BabesiaDiffer from malarial parasite Plasmodium falciparum
in Blood Smear by following points
1Varying shapes and sizes
2Potential to contain vacuoles
3Trophozoites appearing in a tetrad formation
4Lack of pigment production
5Absence of schizonts and gametocytes
Morphologies of Babesia in blood smears

Complications of acute babesiosis –

Complication in Babesiosis is increased in cases of associated – Anemia Hb < 10 gm%

  • renal failure
  • dissemin ated intravascular coagulation (DIC),
  • acute respiratory distress syndrome (ARDS)
  • congestive cardiac failure (CCF)

How the parasite is identified in babesiosis?

  • Parasite can be identified by –
  • Microscopy

amplificarion of babesia1 18S rRNA by PCR is recommended.

Treatment of Babesiosis

1  Atovaquone PLUS azithromycin
2OR – Clindamycin PLUS quinine

Atovaquone 750 mg twice daily, along with azithromycin
500 mg- 1 g/day for a period of 7- 10 days is effective.

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